RESEARCH & ARTICLES

Annotated Regenerative Medicine Articles

Stem Cell Application for Osteoarthritis in the Knee Joint: A Mini Review

  • The aim of this review is to outline the latest advances in stem cell therapy for knee osteoarthritis as well as highlight some of the advantages of stem cell therapy over traditional approaches aimed at restoration of cartilage function in the knee.
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  • Kristin Uth and Dimitar Trifonov

Current Perspectives in Stem Cell Research for Knee Cartilage Repair

  • This review draws attention to the different perspectives on stem cell therapy for repairing damaged cartilage in the knees. It also provides adequate research about the issue with cartilage repair and the role of stem cell therapy during recovery.
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  • Patrick Orth, Ana Rey-Rico, Jagadeesh K Venkatesan, Henning Madry, and Magali Cucchiarini

Clinical Efficacy and Safety of Mesenchymal Stem Cell Transplantation for Osteoarthritis Treatment: A Meta-analysis

  • In this study, the researchers examine the therapeutic efficacy and safety of mesenchymal stem cells (MSCs) for knee osteoarthritis (OA) therapy. It provides significant information about the effectiveness of stem cell therapy for knee osteoarthritis.
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  • Ma Yubo, Li Yanyan, Li Li, Sun Tao, Lin Bo, and Chen Lin

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Advances and Prospects in Stem Cells for Cartilage Regeneration

  • This review examines emerging trends on using stem cells in cartilage tissue repair and regenerative medicine. It focuses on the characterization of cartilage stem cells, the chondrogenic differentiation of stem cells, and the various strategies, approaches, and clinical studies.
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  • Mingjie Wang, Zhiguo Yuan, Ning Ma, Chunxiang Hao, Weimin Guo, Gengyi Zou, Yu Zhang, Mingxue Chen, Shuang Gao, Jiang Peng, Aiyuan Wang, Yu Wang, Xiang Sui, Wenjing Xu, Shibi Lu, Shuyun Liu, and Quanyi Guo

Cartilage Repair by Mesenchymal Stem Cells: Clinical Trial Update and Perspectives

  • This review summarizes recently reported MSC-based clinical trials and discusses new research directions with particular focus on the potential application of MSC-derived extracellular vehicles, miRNAs and advanced gene editing techniques.
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  • Wayne Yuk-wai Lee and Bin Wang

Mesenchymal Stem Cell Therapy in the Treatment of Hip Osteoarthritis

  • This study was performed to investigate the safety and efficacy of the intra-articular infusion of ex vivo expanded autologous bone marrow-derived mesenchymal stem cells (BM-MSC) to a cohort of patients with articular cartilage defects in the hip.
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  • Rodrigo Mardones, Claudio M. Jofré, L. Tobar, José J. Minguell
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